Giulia Federica Mancini

It has been well demonstrated that the exposure to stress can lead to the development of psychiatric diseases (e.g. anxiety, depression, post-traumatic stress disorder). Particularly, experiencing early-life adverse events may exacerbate stress-induced effects in adulthood since the adolescence is a very crucial developmental stage encompassed by profound changes in the structure and function of the brain. My PhD research was focused on the link between stressful experiences and the development of stress related disorders in rats. Currently, my project aims at investigating the potential effectiveness of late glucocorticoid receptors antagonism in reverting the programming effects of early-adolescent stressor, and the neurobiological mechanisms underlying such effects.

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