Systems biology of the Metabolic Syndrome

In addition to bioinformatics and biostatistics we apply functional genetics in combination with mathematical modeling approaches to understand the fluxes of carbohydrates and lipids in vivo. In addition, we are addressing the relation between energy intake and energy expenditure. For example, we are determining the amount of energy that is expended due to movement and food intake (so-called diet induced thermogenesis) in metabolic chamber systems.