Suzan de Boer, PhD

Suzan de Boer joined the group of Jeroen Eikenboom after receiving her doctorate in 2017 at Monash University Melbourne, Australia. Having experience in both immunology and (epi)genetics groups, she started her PhD, focussing on modelling epigenetic dysregulation in developmental disorders. She used Rubinstein-Taybi Syndrome (RTS), a rare congenital genetic disease, to study the genetics and epigenetics underlying this syndrome. Furthermore, she reprogrammed and differentiated fibroblasts of RTS patients into the neuronal lineage to unravel the neurological mechanisms in this syndrome. In combination with a small drug screen, she developed a disease in a dish model to generate potential therapeutic interventions for RTS but also other developmental disorders. At the Einthoven Laboratory, Suzan will be focussing on the structural and functional qualities of blood outgrowth endothelial cells of von Willebrand Disease patients and controls.